%0 Journal Article
%T Identification of two new genes involved in swimming motility of Pseudomonas aeruginosa<br>铜绿假单胞菌泳动能力相关新基因的筛选及鉴定
%A LI Ying-li
%A BAI Fang
%A SHAN Zhi-ying
%A XU Hai-jin
%A QIAO Ming-qiang
%A LIN Wei-li
%A XIA Hui-ming
%A YAO Hong-ming
%A XU Shu-wa
%A ZHANG Xiu-ming
%A BAI Yan-ling
%A <br>李迎丽
%A 白芳
%A 单志英
%A 徐海津
%A 乔明强
%J 微生物学报
%D 2006
%I 
%X Pseudomonas aeruginosa,a typical opportunistic pathogen,has a single polar flagella which provides swimming motility and virulence.Twelve of insertional mutants with Mu transposition complexes into genomic DNA of Pseudomonas aeruginosa were screened on the changes of swimming motility.After gene cloning and DNA sequencing of those mutants,ten of them were illustrated that defective mutations on swimming motility were caused by insertions of Mu transposon into 10 of different functional genes which may involved in biosynthesis of flagella and gene regulations,but another two mutants were resulted from the insertion of two new genes(PA2950,PA5022) with function unknown.Observation of these two mutants with an integrity flagellum under electron microscope showed that two new genes were not involved in construction of flagella,but probably in energy metabolism and gene regulation of swimming motility.
%K Pseudomonas aeruginosa
%K Flagellum
%K Swimming motility<br>铜绿假单胞菌
%K 鞭毛
%K 泳动
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A3C6BA55AB623B90FA9104CFFC826F3C&aid=AD1E6AF79C9B4F5D&yid=37904DC365DD7266&vid=D997634CFE9B6321&iid=CA4FD0336C81A37A&sid=13553B2D12F347E8&eid=BC12EA701C895178&journal_id=0001-6209&journal_name=微生物学报&referenced_num=1&reference_num=16