%0 Journal Article
%T Metabolic engineering strategies for carboxylic acids production by Saccharomyces cerevisiae---a review<br>酿酒酵母生产羧酸的代谢工程策略
%A Guoqiang Xu
%A Liming Liu
%A Jian Chen
%A <br>徐国强
%A 刘立明
%A 陈坚
%J 微生物学报
%D 2011
%I 
%X Carboxylatic acids have been widely used in food,pharmaceutical and chemical industries.As a eukaryotic model organism,Saccharomyces cerevisiae is thought as cell factory to produce organic acids through manipulating metabolic pathway.In this review,we addressed the metabolic engineering strategies to construct a high titer route converting pyruvate to target carboxylate,and to explore how to divert the carbon flux to desired product from ethanol.Furthermore,we also discussed the mechanisms for carboxylate ...
%K Saccharomyces cerevisiae
%K carboxylatic acids
%K metabolic engineering
%K systems biology<br>酿酒酵母
%K 羧酸
%K 代谢工程
%K 系统生物学
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A3C6BA55AB623B90FA9104CFFC826F3C&aid=9345C3E296A5F6AF02AD1CFDDB71C7E8&yid=9377ED8094509821&vid=987EDA49D8A7A635&iid=59906B3B2830C2C5&sid=E7F877B2C3026178&eid=209749DE0D716184&journal_id=0001-6209&journal_name=微生物学报&referenced_num=0&reference_num=37