%0 Journal Article
%T Synergistic inactivation of Bacillus subtilis by high hydrostatic pressure and Nisin at neutral pH<br>中性体系中超高压-Nisin协同作用下的细菌致死机理
%A Weimin Qi
%A Ping Qian
%A Jianyong Yu
%A Xiaojuan Zhang
%A Chiyu Zhang
%A Rongrong Lu
%A <br>戚伟民
%A 钱平
%A 余坚勇
%A 张晓娟
%A 张驰羽
%A 卢蓉蓉
%J 微生物学报
%D 2011
%I 
%X Objective]High hydrostatic pressure (HHP) could be synergized with Nisin in neutral food system to achieve commercial sterilization.The mechanism of synergistic inactivation by HHP treatment and Nisin was investigated at molecular level alongside ultramicroscopic structure.Methods]Bacillus subtilis strain was subjected to HHP (100-500 MPa for 15 min) alone and in combination with Nisin (200 IU /mL) in PBS (pH 7.0).Membrane permeability was studied by fluorescent dye and ultraviolet absorption.Membrane lip...
%K Keywords: high hydrostatic pressure
%K Nisin
%K synergistic inactivation
%K membrane permeability
%K ultramicroscopic structure<br>关键词：超高压
%K 乳酸链球菌素
%K 协同杀菌
%K 细胞膜通透性
%K 超微结构
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A3C6BA55AB623B90FA9104CFFC826F3C&aid=9ECAA2B1D8338A0D74C14D368AF03055&yid=9377ED8094509821&vid=987EDA49D8A7A635&iid=CA4FD0336C81A37A&sid=6209D9E8050195F5&eid=ECE8E54D6034F642&journal_id=0001-6209&journal_name=微生物学报&referenced_num=0&reference_num=44