%0 Journal Article
%T Breeding of High Streptolydigin-Producing Strain by Complex Mutagenesis and Resistance Selection<br>复合诱变和抗性筛选利迪链菌素高产菌株
%A GUO Wei-Huan
%A LI Xiao-Bing
%A YUAN Ying-Jin
%A <br>郭卫寰
%A 李小兵
%A 元英进
%J 微生物学报
%D 2007
%I 
%X 为解决利迪链霉菌生产能力低的问题，以Streptomyces lydicus AS 4.2501-P28为出发菌株，应用紫外和吖啶橙诱变，结合抗生素的抗性筛选，得到稳定高产的S. lydicus AS 4.2501-L8，发酵水平达到177.0 μg/mL，较出发菌株提高了96.2%。
%K Streptomyces lydicus
%K Streptolydigin
%K Complex mutagenesis
%K Resistance selection<br>利迪链霉菌，
%K 利迪链菌素，
%K 复合诱变，
%K 抗性筛选
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A3C6BA55AB623B90FA9104CFFC826F3C&aid=5CC5F87F9CEDE382FDB85D0FE0A19AE1&yid=A732AF04DDA03BB3&vid=339D79302DF62549&iid=94C357A881DFC066&sid=07DFB89828CE2FDB&eid=839CDFF4EF510735&journal_id=0001-6209&journal_name=微生物学报&referenced_num=0&reference_num=0