%0 Journal Article %T Effects of Pprl and RecX on antioxidant activity of Deinococcus radiodumns
PprI和RecX蛋白对耐辐射奇球菌抗氧化作用的影响 %A TIAN Bing %A ZHANG Shao-wen %A XU Zhen-jian %A SHENG Duo-hong %A HUA Yue-jin %A
田兵 %A 张韶文 %A 许镇坚 %A 盛多红 %A 华跃进 %J 微生物学报 %D 2006 %I %X Effects of mutations of PprI(Dr0167) and RecX(Dr1310),which are relative to radioresistance,on reactive oxygen species scavenging activities in Deinococcus radiodurans were investigated using gene mutation,chemiluminescence measurement and enzyme activity analysis.Their possible regulating functions on the activities of antioxidant enzymes was evaluated.Results show that mutant that lacks PprI is remarkably sensitive to reactive oxygen species and its enzyme activities of catalase and superoxide dismutase decrease significantly.On the other hand,RecX has a "negative " effect on reactive oxygen species scavenging activities of this bacterium,i.e.,mutation of recX enhances the scavenging activities on reactive oxygen species,and the enzyme activities of catalase and superoxide dismutase in mutant that lacks RecX are significantly increased.These results indicate that these two genes are relative to the regulation of antioxidant system of this bacterium.It presents some idea to the further investigation on the antioxidant mechanism of this bacterium. %K Deinococcus radiodurans %K PprI %K RecX %K Reactive oxygen species scavenging effects %K Catalase %K Superoxide dismutase
耐辐射奇球菌 %K PprI %K RecX %K 活性氧清除作用 %K 过氧化氢酶 %K 超氧化物歧化酶 %U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A3C6BA55AB623B90FA9104CFFC826F3C&aid=764C2433BB2B949B6F1CF5C79A7C6947&yid=37904DC365DD7266&vid=D997634CFE9B6321&iid=0B39A22176CE99FB&sid=9CA95D22FC1D537C&eid=0C191C6ECF79047F&journal_id=0001-6209&journal_name=微生物学报&referenced_num=0&reference_num=15