%0 Journal Article
%T Molecular regulation of microbial secondary metabolites<br>微生物次生代谢的分子调控
%A Linqi Wang
%A Huarong Tan
%A <br>王琳淇
%A 谭华荣
%J 微生物学报
%D 2009
%I 
%X Abstract: Microbial secondary metabolites play an important role in the field of industry, agriculture, medicine and human health. The molecular regulation of secondary metabolites is gradually becoming noticeable and intriguing. In recent years, many researches have demonstrated that secondary metabolite biosynthesis is tightly linked to the physiological and developmental status in its producer. It is suggested that the biosynthesis of secondary metabolites involves in complex process concerning multi-level regulation. Here we reviewed the recent research progress on the molecular regulation of secondary metabolites in microorganisms. In known about ten thousand kinds of natural secondary metabolites, most of them (about 60%) were produced by Streptomycete. Therefore, the regulation of secondary metabolites in Streptomyces is chosen as the mainline in this review. Additionally, several well-studied antibiotics as the representative members were targeted. Finally, some suggestions, in response to the issues at present, have been presented in this paper.
%K 关键词：微生物
%K 次生代谢
%K 分子调控
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A3C6BA55AB623B90FA9104CFFC826F3C&aid=7717B036C2754FA443261854B1E41284&yid=DE12191FBD62783C&vid=2A3781E88AB1776F&iid=E158A972A605785F&sid=34D9E20AD82A0D72&eid=1FF3CD54EFC256A1&journal_id=0001-6209&journal_name=微生物学报&referenced_num=0&reference_num=40