%0 Journal Article
%T Recombinant Probiotics for Prevention of Enteric Infections<br>转基因益生菌：预防肠道感染的新型微生态制剂
%A LIN Yong
%A YAO Wen
%A ZHU Wei-Yun
%A <br>林 勇
%A 姚 文
%A 朱伟云
%J 微生物学报
%D 2008
%I 
%X Many microbial pathogens, including those responsible for major enteric infections, exploit oligosaccharides that are displayed on the surface of host cells as receptors for toxins and adhesins. Blocking crucial ligand receptor interactions is therefore a promising therapeutic strategy. One approach is to express molecular mimics of host receptors on the surface of harmless recombinant bacteria that can survive in the gut. These recombinant probiotics bind bacterial toxins in the gut lumen with very high avidity, thereby preventing disease.
%K Toxins
%K Recombinant
%K Probiotics<br>类志贺毒素
%K 转基因
%K 益生菌
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A3C6BA55AB623B90FA9104CFFC826F3C&aid=FB2F8072B0C56B36BC1957FD68C52FFA&yid=67289AFF6305E306&vid=6209D9E8050195F5&iid=B31275AF3241DB2D&sid=C28EB3B58FEF7AB1&eid=5944FBFEFE5FF309&journal_id=0001-6209&journal_name=微生物学报&referenced_num=0&reference_num=0