%0 Journal Article
%T Effect of Sodium Citrate on The Growth Metabolism and Inosine Accumulation by Bacillus subtilis<br>柠檬酸钠对枯草杆菌生长代谢及肌苷积累的影响
%A LIU Xin-Xing
%A CHEN Shuang-Xi
%A CHU Ju
%A ZHUANG Ying-Ping
%A ZHANG Si-Liang
%A <br>刘新星
%A 陈双喜
%A 储炬
%A 庄英萍
%A 张嗣良
%J 微生物学报
%D 2004
%I 
%X The effects of sodium citrate on the growth metabolism and inosine accumulation by Bacillus subtillus were studied in this paper.When 0.2% sodium citrate was added into the basal medium,the inosine yield and the yield coefficient of inosine to glucose in the broth were increased 18% and 38% respectively.The analysis on the activities of some key enzymes during inosine fermentation revealed that the supplement of sodium citrate had profound effect on the activity of several key enzymes. The activities of Phosphofructokinase and Pyruvate Kinase were decreased remarkably,the flux of glycolysis pathway was thus cut down as well.
%K Inosine
%K Sodium citrate
%K Pyruvate kinase
%K Glycolysis flux<br>肌苷
%K 柠檬酸钠
%K 丙酮酸激酶
%K 糖酵解通量
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A3C6BA55AB623B90FA9104CFFC826F3C&aid=C4F1B371320C85ED&yid=D0E58B75BFD8E51C&vid=1AE5323881A5ECDC&iid=94C357A881DFC066&sid=821800203AD09E7B&eid=039DCCB9394D9766&journal_id=0001-6209&journal_name=微生物学报&referenced_num=9&reference_num=10