%0 Journal Article
%T The application and research advances of Brucella vaccines<br>布氏杆菌病疫苗的应用和研究现状
%A DING Jia-bo
%A MAO Kai-rong
%A CHENG Jun-sheng
%A DAI Zhi-hong
%A JIANG Yu-wen
%A <br>丁家波
%A 毛开荣
%A 程君生
%A 戴志红
%A 蒋玉文
%J 微生物学报
%D 2006
%I 
%X Brucellosis is a crucial zoonosis caused by Brucella,which has some traits of wide hosts,great infectivity and difficulty in cure.Brucellosis caused great losses to farming and people's health.Vaccination is the main measure used to control Brucellosis,and some attenuated Brucella strains were often used as vaccines.To find more effective vaccines,Scientists are now constructing recombinant strains,DNA vaccines and subunit vaccines,as well as inducing new attenuated strains from isolations.The present applications of B.abortus strain 19(S19),B.melitensis Rev.1(Rev.1),B.suis strain 2(S2),B.abortus strain 45/20(45/20) and rough strain B.abortus 51(RB51) were discussed.And some recent research work on Brucella vaccines,such as Brucella recombinant vaccines,DNA vaccines and so on,were reviewed in this paper.
%K Brucella
%K Brucellosis
%K Vaccine<br>布氏杆菌
%K 布氏杆菌病
%K 疫苗
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A3C6BA55AB623B90FA9104CFFC826F3C&aid=DBD8BDF516F8EB2B&yid=37904DC365DD7266&vid=D997634CFE9B6321&iid=94C357A881DFC066&sid=353B961D86F026C0&eid=EE7D0B10C851F35D&journal_id=0001-6209&journal_name=微生物学报&referenced_num=13&reference_num=26