%0 Journal Article
%T Determination of Angptl4 mRNA as a Diagnostic Marker of Primary and Metastatic Clear Cell Renal-Cell Carcinoma
%A J¨¦r£¿me Verine
%A Jacqueline Lehmann-Che
%A Hany Soliman
%A Jean-Paul Feugeas
%A Jean-S¨¦bastien Vidal
%A Pierre Mongiat-Artus
%A St¨¦phanie Belhadj
%A Josette Philippe
%A Matthieu Lesage
%A Evelyne Wittmer
%A St¨¦phane Chanel
%A Anne Couvelard
%A Sophie Ferlicot
%A Nathalie Rioux-Leclercq
%A Jean-Michel Vignaud
%A Anne Janin
%A St¨¦phane Germain
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0010421
%X We have previously shown that angiopoietin-like 4 (angptl4) mRNA, a hypoxia-inducible gene, is highly expressed in clear cell renal-cell carcinoma (ccRCC), the most common subtype of RCC for which no specific marker is available. We here investigated whether angptl4 mRNA 1) could be a useful diagnostic and/or prognostic marker of ccRCC in a large and comprehensive retrospective series, 2) induction is dependent on the VHL status of tumors.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0010421