%0 Journal Article
%T Review on molecular mechanisms of Saccharomyces cerevisiae inhibitor tolerance during cellulosic ethanol production<br>酿酒酵母在纤维素乙醇生产中对毒性化合物的耐受机理研究进展
%A HAO Xue-Cai
%A MEN Xun
%A ZHANG Yi
%A YANG Fei
%A CAO Meng
%A ZHAI Dong-Mei
%A TIAN Shen
%A <br>郝学才
%A 门珣
%A 张宜
%A 杨非
%A 曹萌
%A 翟冬梅
%A 田沈
%J 微生物学通报
%D 2012
%I 
%X Pretreatment of lignocellulosic materials for ethanol production generates inhibitory compounds that interfere with microbial growth and subsequent fermentation. To facilitate fermentation process, detoxification techniques have been commonly applied to remediate these inhibitory compounds. However, these additional steps result in sugar loss and an extra cost in practice. To meet desired overall yields during ethanol production, it is of great practi-cal importance to improve the inhibitor-tolerance of Saccharomyces cerevisiae. In the last decade, significant progress has been made in understanding the mechanisms of yeast stress tolerance. This article reviewed the molecular mechanisms of Sacchromyces cerevisiae inhibi-tor tolerance focusing on its enhanced expression and pathway analysis of some key genes. We also discussed the strategies for improving the fermentation performance of yeast.
%K Inhibitor
%K Stress tolerance
%K Gene expression
%K Pathway analysis<br>发酵抑制剂
%K 耐受性
%K 基因表达
%K 代谢通路分析
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=78024727B5F4EF6AA9CA8E605B5FC464&aid=C3C9E433FF4C68C4FDB58703E8D74D6D&yid=99E9153A83D4CB11&vid=7C3A4C1EE6A45749&iid=0B39A22176CE99FB&sid=81EB57889E049393&eid=6A8C095CA31F730A&journal_id=0253-2654&journal_name=微生物学通报&referenced_num=0&reference_num=32