%0 Journal Article
%T Analysis of Tetracycline-Resistant Aeromonas hydrophlia by Proteome Techniques<br>嗜水气单胞菌耐四环素的蛋白质组学初步研究
%A CHEN Chuan WANG San-Ying PENG Xuan-Xian
%A <br>陈川
%A 王三英
%A 彭宣宪
%J 微生物学报
%D 2004
%I 
%X In the article, the tetracycline-resistant Aeromonas hydrophlia was selected with antibiotic sub-inhibitory concentration of tetracycline. MIC of the resistant strains was eight times the original strains. To compare with 2-D PAGE of original strains, three proteins were achieved expressing conspicuous variances in resistant strains. By MALDI-TOF-MS and the Peptident software in the SWISS-PROT database, the variances were analyzed and elementarily identified as relevant with ribosomal small unit proteins, drug-discharged system proteins and acetate CoA-transferase beta subunit respectively. Besides, the resistant mechanism of Aeromonas hydrophlia was elementarily studied.
%K Two-dimensional electrophoresis
%K MALDI-TOF-MS
%K Tetracycline-resistant
%K Aeromonas hydrophlia<br>双向电泳，
%K MALDITOF，四环素，耐药性，嗜水气单胞菌
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A3C6BA55AB623B90FA9104CFFC826F3C&aid=8C6334E330366D82&yid=D0E58B75BFD8E51C&vid=1AE5323881A5ECDC&iid=38B194292C032A66&sid=7D6CD8918B045FD4&eid=4F0B2F798E08B761&journal_id=0001-6209&journal_name=微生物学报&referenced_num=4&reference_num=12