%0 Journal Article
%T POLYMORPHISM AND POLOGENETIC AFFINITIES OF GENOTYPE IN PATHOGENIC YEAST<br>致病酵母菌基因组多态性及亲缘关系的研究
%A Li Dongmei Wang Duanli Li Shiyin Li Ruoyu
%A <br>李冬梅
%A 王端礼
%A 李世荫
%A 李若瑜
%A 朱衡
%A 朱立煌
%J 微生物学报
%D 1997
%I 
%X The classification of pathogenic yeast, which is one of the most common reasons of opportunistic infection in human body, will be useful for the epidemiological survey and clinical works. The genotypic polymorphism of intergenus, interspecies and intraspecies in 48 isolates, including Candida, Cryptococcus, Torulopsis, Trichosporon, Saccaromyces had been administered carefully with patterns amplified by RAPD (Randomly amplified polymorphic DNA) in 53 primers. The pologenetic affinities had been evaluated by similarity coefficients obtained from these profiles. The results indicated that there are significant difference among intergenus, interspecies and intraspecies in Candida and related yeast. The similarity coefficients among Candida and Crytococcus, Trichosporon were maintained about 80%; The similarity coefficients among interspecies of Candida ranged from 82% - 87%, and ones of intraspecies of different Candida species were more than 90%. The genotypic typing of species except C. guilliermondii seems to be related to morphological classification.
%K Yeast
%K Classification
%K Genotype
%K Polymorphism
%K Polygenetic relation<br>酵母
%K 分类
%K 基因组分型
%K 多态性
%K 亲缘关系
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A3C6BA55AB623B90FA9104CFFC826F3C&aid=72CD0394B7CA24DE844BE2AFD90ECB9A&yid=5370399DC954B911&vid=42425781F0B1C26E&iid=0B39A22176CE99FB&sid=5E25104E99903E8A&eid=A8DE7703CC9E390F&journal_id=0001-6209&journal_name=微生物学报&referenced_num=6&reference_num=3