%0 Journal Article
%T Preparation of Chiral Alcohol by Stereoselective Reduction of Acetophenone and Chloroacetophenone with Yeast Cells<br>微生物法还原氯代苯乙酮制备手性醇
%A Ou Zhimin Wu Jianping Yang Lirong
%A Cen Peilin
%A <br>欧志敏
%A 吴坚平
%A 杨立荣
%A 岑沛霖
%J 微生物学报
%D 2003
%I 
%X Four strains of microorganisms which have activity of chloroacetophenone reduction were screened, in which Saccharomyces cerevisiae B5 showed the highest activity and good stereoselectivity. This strains showed different activity on the reduction of various substrates in the following order: 2'-chloroacetophenone > 2-chloromethylacetophenone > 4'-chloroacetophenone > 3'-chloroacetophenone > acetophenone. Ethanol is the best cosubstrate and its optimal concentration is 5%.
%K Chloroacetophenone
%K Stereoselective reduction
%K Chiral alcohol<br>氯代苯乙酮，选择性还原，手性醇
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A3C6BA55AB623B90FA9104CFFC826F3C&aid=D3BBF10702539BAC&yid=D43C4A19B2EE3C0A&vid=BE33CC7147FEFCA4&iid=E158A972A605785F&sid=C81D738643975BB0&eid=E3D3D8D1B650AE1E&journal_id=0001-6209&journal_name=微生物学报&referenced_num=3&reference_num=10