%0 Journal Article
%T Effects of H2 O2 Addition on Cell Growth and Product Formation in Long-chain Dicarboxylic Acid Fermentation<br>二元酸发酵过程中流加H2O2对细胞色素P450酶及产物生成的影响
%A Li Shuliang Hua Yutao Huang Yingming Jiao Peng Cao Zhu''''an
%A <br>李书良
%A 华玉涛
%A 黄英明
%A 焦鹏
%A 曹竹安
%J 微生物学报
%D 2002
%I 
%X When Candida tropicalis was cultivated in shakig-flask with the H 2O 2 addition, DCA (Dicarboxylic Acid,DCA) concentration was increased, especially at 2mmol/L H 2O 2 concentration. The cytochrome P450 activity assays indicated that H 2O 2 addition significantly increased the activities of cytochrome P450 and DCA production positively correlated with the activities of cytochrome P450. The study on the cell growth demonstrated that the H 2O 2 addition inhibited the cell growth rate. However, the retarding effect was not irreversible since the cell growth rate could recover slowly to the original level after the H 2O 2 addition was halted. The mechanism of inducement on cytochrome P450 by H 2O 2 addition was also discussed in this article.
%K Candida tropicalis
%K Long chain dicarboxylic acid
%K Hydrogen peroxide(H
%K 2O
%K 2)
%K Cytochrome P450<br>热带假丝酵母，
%K 长链二元酸，
%K H2O2，
%K 细胞色素P450酶
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A3C6BA55AB623B90FA9104CFFC826F3C&aid=58C24B59F7497086&yid=C3ACC247184A22C1&vid=ECE8E54D6034F642&iid=38B194292C032A66&sid=3356A7630A93A219&eid=8C27CCA578E52082&journal_id=0001-6209&journal_name=微生物学报&referenced_num=2&reference_num=14