%0 Journal Article
%T Regulation of PrfA-dependent Virulence Genes Expression in Listeria monocytogenes<br>单核细胞增生李斯特菌PrfA蛋白转录调控毒力基因表达的分子机制
%A LUO Qin
%A ZHANG Xiao-Li
%A LI Bing
%A FENG Ai-Ping
%A QIAN Yue
%A <br>罗 勤
%A 张晓莉
%A 李 兵
%A 冯爱平
%A 钱 跃
%J 微生物学通报
%D 2008
%I 
%X The gram-positive, facultative intracellular bacterium Listeria monocytogenes belongs to one of four severe food-borne pathogens issued by WHO. It is not only a causal agent of listeriosis caused infection of humans and animals, but also an important model system for the study of intracellular pathogens. Most of well-known listerial virulence genes are regulated by PrfA. The LM virulence genes involved in the infectious process and the PrfA-dependent virulence genes expression as well as putative regulative mechanisms were introduced and analyzed in this paper.
%K Listeria monocytogenes
%K PrfA
%K Virulence gene
%K Regulation<br>单核细胞增生李斯特菌
%K PrfA
%K 蛋白
%K 毒力基因
%K 表达调控
%K 单核
%K 细胞增生
%K 李斯特菌病
%K PrfA
%K 调节蛋白
%K 转录调控
%K 毒力基因
%K 基因表达
%K 分子机制
%K Listeria
%K monocytogenes
%K Expression
%K Genes
%K Virulence
%K 结构和功能
%K 重点
%K 宿主细胞
%K 侵染
%K 转录表达
%K 细菌
%K 模式
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=78024727B5F4EF6AA9CA8E605B5FC464&aid=094D5317AC450FF69E1C3BCB03ECE4F3&yid=67289AFF6305E306&vid=6209D9E8050195F5&iid=0B39A22176CE99FB&sid=5F626951286672A3&eid=C6B5659702541F3C&journal_id=0253-2654&journal_name=微生物学通报&referenced_num=5&reference_num=24