%0 Journal Article
%T Host-virus Interaction at the miRNA Level<br>宿主-病毒在miRNA水平上的相互作用
%A ZHENG Yu-Shu
%A ZHAO Pu
%A JIA Bei-Bei
%A LIU Xing-You
%A <br>郑玉姝
%A 赵 朴
%A 贾贝贝
%A 刘兴友
%J 微生物学通报
%D 2008
%I 
%X MicroRNAs (miRNAs) are recently discovered major regulators of gene expression, which play a pivotal role in a wide spectrum of biological processes including antiviral defence. There is growing evidence that some viruses either encode their own viral miRNAs or subvert cellular miRNAs. The host- and virus-encoded miRNAs and their targets together thus form a novel regulatory layer of interactions between the host and the virus. A better understanding of host-virus interaction mediated by miRNAs would not only enable us to unravel the molecular basis of viral pathogenesis, but also enable us to develop better therapeutic strategies.
%K Host
%K Virus
%K Interaction
%K miRNA<br>宿主
%K 病毒
%K 相互作用
%K miRNA
%K 宿主
%K 病毒
%K miRNAs
%K 水平
%K 相互作用
%K Level
%K 治疗策略
%K 分子基础
%K 调节子
%K 靶标
%K 细胞
%K 编码
%K 证据
%K 防御
%K 生物学过程
%K 基因
%K 发现
%K microRNA
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=78024727B5F4EF6AA9CA8E605B5FC464&aid=0E8BFAD51D36590D40723C1CD6662C38&yid=67289AFF6305E306&vid=6209D9E8050195F5&iid=DF92D298D3FF1E6E&sid=CF89D3C02791C82E&eid=F9AB8F3D624A89DB&journal_id=0253-2654&journal_name=微生物学通报&referenced_num=1&reference_num=13