%0 Journal Article
%T A Study on the Streptomycin-resistant(STR)Mutational Screening of High-yield Micronomicin Strain<br>通过获得链霉素抗性基因突变株筛选小诺霉素高产菌株
%A TU Guo Quan
%A ZHONG Cheng Zan
%A HUANG Lin
%A HUANG Luo Jia
%A WENG Juan
%A <br>涂国全
%A 钟承赞
%A 黄林
%A 黄珞珈
%A 翁娟
%J 微生物学通报
%D 2004
%I 
%X After testing the resistance of streptomycin to Micromonospora purpura No 49 12,a lot of streptomycin resistant(str)mutants were screened after the spores regenerated on the lethal media when they were treated with 3 different dosage of super mutageng EMS We have abtained the high yield strain 49 12 13 from these str mutants which the productivity is beyond 40% higher than the original strain's in the rotation flask experiments The ratio between C 2b and C 1a in the micronomicin has been increased 5:5 to 8:2, the effective component of C 2b is 30% more than the original strain's It was showed that the streptomycin resistance mutation of the strains had closely relation with the yield mutation of the micrnomicin, and the rate of 40% of the positive mutation is larger than the rate of 26% of the negtive nutation
%K Micromonospora purpura
%K Micronomicin
%K The screening of streptomycin
%K resistance mutants<br>降红小单孢菌
%K 小诺霉素
%K 链霉菌抗性基因突变筛选
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=78024727B5F4EF6AA9CA8E605B5FC464&aid=4F4BEB1D5A4E894E&yid=D0E58B75BFD8E51C&vid=4AD960B5AD2D111A&iid=E158A972A605785F&sid=2A8D03AD8076A2E3&eid=BC12EA701C895178&journal_id=0253-2654&journal_name=微生物学通报&referenced_num=1&reference_num=7