%0 Journal Article %T Deficiency of the LIM-Only Protein FHL2 Reduces Intestinal Tumorigenesis in Apc Mutant Mice %A Charlotte Labalette %A Yann Nou£¿t %A Florence Levillayer %A Sabine Colnot %A Ju Chen %A Valere Claude %A Michel Huerre %A Christine Perret %A Marie-Annick Buendia %A Yu Wei %J PLOS ONE %D 2012 %I Public Library of Science (PLoS) %R 10.1371/journal.pone.0010371 %X The four and a half LIM-only protein 2 (FHL2) is capable of shuttling between focal adhesion and nucleus where it signals through direct interaction with a number of proteins including ¦Â-catenin. Although FHL2 activation has been found in various human cancers, evidence of its functional contribution to carcinogenesis has been lacking. %U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0010371