%0 Journal Article
%T Advances in Gene-engineering Production of Defensins<br>防御素基因工程制备研究进展
%A WANG Ai-Ping
%A WANG Jun-Ping
%A SU Yong-Ping
%A <br>王艾平
%A 王军平
%A 粟永萍
%J 微生物学通报
%D 2008
%I 
%X This paper reviews the recent advances in recombinant expression and purification of defensins, including the choice of host cells, vectors and expression strategies in prokaryotic and eukaryotic cell expression systems, as well as the status of purification processes. By summarizing the problems existed in the production and clinical applications of defensins, the authors here also pointed out the research directions for defensins, and conceived the prospects for its exploitation in the future.
%K Defensins
%K Recombinant expression
%K Purify process
%K Bioactivity<br>防御素
%K 重组表达
%K 纯化工艺
%K 生物活性
%K 防御素
%K 基因工程
%K 研究进展
%K Production
%K 前景
%K 开发
%K 方向
%K 问题
%K 临床应用
%K 现状
%K 纯化
%K 重组表达
%K 真核细胞
%K 酵母等
%K 的选择
%K 表达策略
%K 载体
%K 宿主菌
%K 原核细胞表达
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=78024727B5F4EF6AA9CA8E605B5FC464&aid=337DC19EEB12DE53189349B75E6DF1B2&yid=67289AFF6305E306&vid=6209D9E8050195F5&iid=38B194292C032A66&sid=523FF5E3C048C85E&eid=9A9313F7A5E45609&journal_id=0253-2654&journal_name=微生物学通报&referenced_num=0&reference_num=90