%0 Journal Article %T ¦Á-Hydroxybutyrate Is an Early Biomarker of Insulin Resistance and Glucose Intolerance in a Nondiabetic Population %A Walter E. Gall %A Kirk Beebe %A Kay A. Lawton %A Klaus-Peter Adam %A Matthew W. Mitchell %A Pamela J. Nakhle %A John A. Ryals %A Michael V. Milburn %A Monica Nannipieri %A Stefania Camastra %A Andrea Natali %A Ele Ferrannini %J PLOS ONE %D 2012 %I Public Library of Science (PLoS) %R 10.1371/journal.pone.0010883 %X Insulin resistance is a risk factor for type 2 diabetes and cardiovascular disease progression. Current diagnostic tests, such as glycemic indicators, have limitations in the early detection of insulin resistant individuals. We searched for novel biomarkers identifying these at-risk subjects. %U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0010883