%0 Journal Article
%T Dissecting the Clinical Heterogeneity of Autism Spectrum Disorders through Defined Genotypes
%A Hilgo Bruining
%A Leo de Sonneville
%A Hanna Swaab
%A Maretha de Jonge
%A Martien Kas
%A Herman van Engeland
%A Jacob Vorstman
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0010887
%X The etiology of autism spectrum disorders (ASD) is largely determined by different genetic factors of variable impact. This genetic heterogeneity could be a factor to explain the clinical heterogeneity of autism spectrum disorders. Here, a first attempt is made to assess whether genetically more homogeneous ASD groups are associated with decreased phenotypic heterogeneity with respect to their autistic symptom profile.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0010887