%0 Journal Article
%T Bacteriophage Lysins: A Novel Effective Antibacterial Agents<br>噬菌体裂解酶——现状与未来
%A FANG Yuan-Zi
%A WANG Yan
%A SUN Jian-He
%A <br>方圆子
%A 王 琰
%A 孙建和
%J 微生物学通报
%D 2009
%I 
%X Lysins are efficient bacteria cell wall digesting enzymes encoded by DNA bacteriophage. Gram-positive bacteriophage lysins feature similar domain structure, high lytic efficiency, synergic antibacterial effect with antibiotics, rare neutralization by antibodies, less chance of developing drug-resistant strains, et al. The past decade has seen a considerable amount of research worldwidely focused on lysin, and lysins have been used successfully in a variety of animal models to control pathogenic antibiotic resistant bacteria found on mucosal surfaces and infected tissues. The great potential of lysins as an anti-infective agent prompted this review.
%K Bacteriophage
%K Lysin<br>噬菌体
%K 裂解酶
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=78024727B5F4EF6AA9CA8E605B5FC464&aid=54DCCD8F6B13E83817126AB1210123E3&yid=DE12191FBD62783C&vid=933658645952ED9F&iid=59906B3B2830C2C5&sid=3A61856D91CF5877&eid=27DC88857EA57257&journal_id=0253-2654&journal_name=微生物学通报&referenced_num=0&reference_num=0