%0 Journal Article
%T STUDIES ON pH CONTROLLED FERMENTATION OF BIOACTIVE EXOPOLYSACCHARIDES BY GANODERMA LUCIDUM<br>灵芝胞外生物活性多糖的pH控制发酵
%A LI Ping-Zuo
%A ZHANG Ke-Chang
%A <br>李平作
%A 章克昌
%J 微生物学通报
%D 2000
%I 
%X The effect of fermentation pH upon exopolysaccharides production by Ganoderma lucidum was studied in a 2L fermentor. The results showed that initial pH5.5 was favorable to exopolysaccharides production. Through an effective strategy of pH controlled fermentation at pH4.0, the maximum yield of exopolysaccharides, 2.32g/L, was obtained, and the yield of exopolysaccharides increased by 24% compared with the pH uncontrolled fermentation. The bioactivities of exopolysaccharides were also assayed. The results showed that exopolysaccharides could inhibit the growth of Sarcoma 180 in mice, and the average inhibition ratio (i.p. 10mg/kg for 10 days) was 51.2%; the immunological activity of mice could be significantly improved.
%K Ganoderma lucidum
%K pH controlled fermentation
%K Exopolysaccharides
%K Bioactivities<br>灵芝
%K pH控制发酵
%K 胞外多糖
%K 生物活性
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=78024727B5F4EF6AA9CA8E605B5FC464&aid=1A1B893116BDC412&yid=9806D0D4EAA9BED3&vid=DB817633AA4F79B9&iid=CA4FD0336C81A37A&sid=94C357A881DFC066&eid=5D311CA918CA9A03&journal_id=0253-2654&journal_name=微生物学通报&referenced_num=37&reference_num=10