%0 Journal Article
%T A Meta Analysis of Randomized Controlled Study on DPN Treatment by Danhong Injection Combined with Mecobalamin<br>丹红注射液联合甲钴胺治疗糖尿病周围神经病变随机对照试验的Meta 分析
%A Wang Rongrong
%A Zhang Chunmiao
%A Cao Lei
%A Pan Fei
%A <br>王荣荣
%A 张春苗
%A 曹蕾
%A 潘飞
%J 世界科学技术-中医药现代化
%D 2011
%I 
%X The study was aimed to evaluate the efficacy and safety of Danhong injection combined with Mecobalamin in DPN treatment. Domestic published literatures of randomized controlled clinical trials in DPN treatment by Danhong injection combined with Mecobalamin were searched and selected. Meta analysis was used in the statistical analysis. The results showed that a total of 14 studies met the inclusion criteria. And 1019 patients of DPN were included. Compared with control group, the results of meta analysis showed that the clinical comprehensive curative effect was superior in DPN treatment by Danhong injection combined with Mecobalamin OR=4.01, 95%CI (2.90-5.53)], the conduction velocity of peripheral nerves, including motor nerve in median nerves WMD=3.81, 95%CI (3.29, 4.34)], sensory nerve in median nerves WMD=3.94, 95%CI (3.32, 4.55)], motor nerve in peroneal nerves WMD=3.71, 95%CI (3.21, 4.21)], sensory nerve in peroneal nerves WMD=6.13, 95%CI (5.59, 6.68)] were improved, as well as plasma viscosity WMD=-0.50, 95%CI (-0.58, -0.42)]. It was concluded that Danhong injection combined with Mecobalamin in DPN treatment was more effective than the control group, especial on the improvement of conduction velocity of peripheral nerves and plasma viscosity. There was no serious adverse event in the above trails. The symptoms of 3 cases of adverse events founded were rash, chest tightness and dizziness respectively.
%K Danhong injection
%K Mecobalamin
%K DPN
%K Meta analysis<br>丹红注射液，甲钴胺，糖尿病周围神经病变，Meta分析
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=A9DB1C13C87CE289EA38239A9433C9DC&cid=B5F35A1FC27C1FF7&jid=44257A35316DB0727BA6BC707B9EDAAB&aid=656E32E02735604B8DF2A77B765DDCBD&yid=9377ED8094509821&vid=FC0714F8D2EB605D&iid=B31275AF3241DB2D&sid=E062BF8B95A95FD2&eid=126825C4749D880D&journal_id=1674-3849&journal_name=世界科学技术-中医药现代化&referenced_num=0&reference_num=0