%0 Journal Article
%T Transdermal Behavior of Geniposide in Shangyi Aerosol in vivo and in vitro<br>彝族药伤益气雾剂中栀子苷透皮吸收的动力学观察
%A Zhan Honglei
%A Wang Yugang
%A Zhu Zhaoyun
%A Hua Lei
%A Zhao Yi
%A Xu Rongxue
%A Lei Fan
%A Du Lijun
%A <br>詹宏磊
%A 王玉刚
%A 朱兆云
%A 花 雷
%A 赵 毅
%A 徐榕雪
%A 雷 帆
%A 杜力军
%J 世界科学技术-中医药现代化
%D 2010
%I 
%X The transdermal behavior of geniposide was observed by using Shangyi aerosol for mice, and of the geniposide pharmacokinetics of this aerosol was studied. The geniposide concentration was determined in vitro and in vivo by the HPLC assay. Geniposide penetrated the skin 30 min after the aerosol use, and was found distributed in the hypodermis and the blood. The penetration of geniposide showed a positive linear relation. The results showed that geniposide of Shangyi aerosol could penetrate the skin both in vivo and in vitro, and be quickly distributed in the subcutaneous tissue and blood, which shows the use potential of the aerosol in clinics.
%K Geniposice
%K Transdermal<br>栀子苷
%K 透皮吸收
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=A9DB1C13C87CE289EA38239A9433C9DC&cid=B5F35A1FC27C1FF7&jid=44257A35316DB0727BA6BC707B9EDAAB&aid=656E32E02735604B1000E1AA50540F03&yid=140ECF96957D60B2&vid=59906B3B2830C2C5&iid=38B194292C032A66&sid=09AA1448D1EAF9C1&eid=84A93BA251D28205&journal_id=1674-3849&journal_name=世界科学技术-中医药现代化&referenced_num=1&reference_num=0