%0 Journal Article
%T Identification of Active Compounds and Potential Targets of Xue-Fu-Zhu-Yu-Tang<br>基于中药有效成分族辨识的血府逐瘀汤配伍研究
%A Zhang Yanling
%A Huang Mingfeng
%A Wang Yuanming
%A Gao Jing
%A Qiao Yanjiang
%A <br>张燕玲
%A 黄明峰
%A 王元明
%A 高静
%A 乔延江
%J 世界科学技术-中医药现代化
%D 2012
%I 
%X Identification Technology of Active Clusters (ITAC) was used to reveal the compatibility of Xue-Fu-Zhu-Yu-Tang (XFZY). All 668 compounds were found from XFZY, and 58 pharmacophores were used to identify active compounds. All 213 compounds and 20 targets were identified. Most of the function of the targets related to cardiovascular disease, inflammation and cancer. Compound-target interaction network was constructed by Cytoscape. Then, the mechanism of the multi-compounds act on multi-targets was analyzed to reveal the mechanism of prevention and treatment on coronary heart disease by XFZY. New potential indications of XFZY were also suggested by this paper.
%K 有效成分族辨识
%K 血府逐瘀汤
%K 方剂配伍
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=A9DB1C13C87CE289EA38239A9433C9DC&cid=B5F35A1FC27C1FF7&jid=44257A35316DB0727BA6BC707B9EDAAB&aid=1DCBC9D46FCE71EF9BDF34DFF074A373&yid=99E9153A83D4CB11&vid=F3583C8E78166B9E&iid=E158A972A605785F&sid=3F94E028184E4B65&eid=3CF1C8D14DE283F7&journal_id=1674-3849&journal_name=世界科学技术-中医药现代化&referenced_num=0&reference_num=0