%0 Journal Article %T Identification of Chemical and Metabolic Components of Liuwei Dihuang Pills by Ultra Fast Liquid Chromatography-Electrospray-Ion Trap-Time of Flight Mass Spectrometry
UFLC-ESI-IT-TOF鉴定六味地黄丸中的化学成分和代谢成分 %A Zhao Xinfeng %A Kong Hongwei %A Wang Jiangshan %A Xu Guowang %A
赵新峰 %A 孔宏伟 %A 汪江山 %A 许国旺 %J 世界科学技术-中医药现代化 %D 2009 %I %X Objective: To identify the chemical and metabolic components. Method: UFLC gradient elution with TOF detection in positive and negative mode. Result: 40 chemical components were identified in Liuwei Dihuang extract. 6 original component and 9 metabolites were identified in rat serum. The proposed metabolic pathway was given. Conclusion: UFLC-ESI-IT-TOF was a powerful method in the analysis of complicated TCM samples. It helps the comprehensive understanding of the chemical and metabolic components of Liuwei Dihuang Pills. %K UFLC-ESI-IT-TOF %K Liuwei Dihuang Pills %K Chemical Components %K Metabolic Components
超快液相色谱 %K 飞行时间质谱 %K 六味地黄丸 %K 化学成分 %K 代谢成分 %U http://www.alljournals.cn/get_abstract_url.aspx?pcid=A9DB1C13C87CE289EA38239A9433C9DC&cid=B5F35A1FC27C1FF7&jid=44257A35316DB0727BA6BC707B9EDAAB&aid=29C0764AAC1C331F6CF6F628DFD3895D&yid=DE12191FBD62783C&vid=708DD6B15D2464E8&iid=CA4FD0336C81A37A&sid=D59111839E7C8BDF&eid=0B4F496D54044D86&journal_id=1674-3849&journal_name=世界科学技术-中医药现代化&referenced_num=1&reference_num=0