%0 Journal Article %T Methodological Deficits in Diagnostic Research Using ¡®-Omics¡¯ Technologies: Evaluation of the QUADOMICS Tool and Quality of Recently Published Studies %A Lucy A. Parker %A Noem¨ª G¨®mezSaez %A Blanca Lumbreras %A Miquel Porta %A Ildefonso Hern¨¢ndez-Aguado %J PLOS ONE %D 2012 %I Public Library of Science (PLoS) %R 10.1371/journal.pone.0011419 %X QUADOMICS is an adaptation of QUADAS (a quality assessment tool for use in systematic reviews of diagnostic accuracy studies), which takes into account the particular challenges presented by ¡®-omics¡¯ based technologies. Our primary objective was to evaluate the applicability and consistency of QUADOMICS. Subsequently we evaluated and describe the methodological quality of a sample of recently published studies using the tool. %U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0011419