%0 Journal Article
%T Themis2/ICB1 Is a Signaling Scaffold That Selectively Regulates Macrophage Toll-Like Receptor Signaling and Cytokine Production
%A Matthew J. Peirce
%A Matthew Brook
%A Nicholas Morrice
%A Robert Snelgrove
%A Shajna Begum
%A Alessandra Lanfrancotti
%A Clare Notley
%A Tracy Hussell
%A Andrew P. Cope
%A Robin Wait
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0011465
%X Thymocyte expressed molecule involved in selection 1 (Themis1, SwissProt accession number Q8BGW0) is the recently characterised founder member of a novel family of proteins. A second member of this family, Themis2 (Q91YX0), also known as ICB1 (Induced on contact with basement membrane 1), remains unreported at the protein level despite microarray and EST databases reporting Themis2 mRNA expression in B cells and macrophages.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0011465