%0 Journal Article
%T Effects of 1,2,4-trichlorobenzene on the Growth and Ultrastructure of the Skin and Intestinal Epithelium of Earthworm<br>1,2,4-三氯苯对蚯蚓生长和表皮及肠道超微结构的影响
%A Li Huilong
%A Lei Zhen
%A Wu Ermiao
%A Hu Yan
%A Wu Shijin
%A <br>李辉龙
%A 雷震
%A 吴尔苗
%A 胡艳
%A 吴石金
%J 生态毒理学报
%D 2011
%I 
%X The mortality, growth and ultrastructural changes of the intestinal epithelium in earthworms (Eisenia fetida) that were exposed to the soil with different doses of 1,2,4-TCB by acute exposure test were investigated. The results showed that the median lethal concentrations (LC 50) of the earthworms exposed to 1,2,4-TCB was 890.295 mg·kg-1 for 14 days. 1,2,4-TCB inhibited the growth of earthworms during the test, and the inhibition rates were positively correlated with exposure time and 1,2,4-TCB dosage. Both exposure time and 1,2,4-TCB dosage had significant effects to the inhibition rates, but there was no significant interaction between them. Epidermis secretory cells increased, thickened, epicuticle damaged, intestinal epithelial caved in and formed ulcer surfaces or lacerated when the earthworms were exposed to 50 mg?kg-1 1,2,4-TCB. After exposure for 14 days, the damage of epicuticle and intestinal epithelial recovered a bit. Thickened and secretory cells increased obviously, intestinal epithelial lacerated and shed when the earthworms were exposed to 400 mg·kg-1 1,2,4-TCB. Thinner and epidermis secretory cells became fewer, epicuticle damaged, intestinal epithelial lacerated and shed seriously in 14 days' exposure. The ultrastructure of intestinal epithelium in 14 days' exposure revealed that cristae of mitochondria was not clear or broken and mitochondria confused at 50 mg·kg-1 1,2,4-TCB; some mitochondria vacuoled or appeared flocculent precipitate, cristae shortened or even disappeared at 400 mg·kg-1 1,2,4-TCB.
%K 1
%K 2
%K 4-trichlorobenzene
%K Eisenia fetida
%K epidermal
%K intestinalep ithelium
%K ultrastructure
%K ecotoxicity<br>1
%K 2
%K 4-三氯苯
%K 赤子爱胜蚓
%K 表皮
%K 肠道
%K 超微结构
%K 生态毒理
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=3FF3ABA7486768130C3FF830376F43B398E0C97F0FF2DD53&cid=BEC1F4700DD66C14D137590A0896A0AD&jid=B98D390DF92C35E6DD1987675E4EE86E&aid=C5FFE4667A315463E9B56F2404DCB2AE&yid=9377ED8094509821&vid=B31275AF3241DB2D&iid=38B194292C032A66&sid=002786F01A86D891&eid=01622E3E475F966C&journal_id=1673-5897&journal_name=生态毒理学报&referenced_num=0&reference_num=24