%0 Journal Article
%T Toxicities of Selected Ionic Liquids and Their Mixtures to Photobacteria (Vibrio-qinghaiensis sp. -Q67)<br>部分离子液体及其混合物对发光菌的毒性作用
%A LIU Fang
%A LIU Shu-shen
%A LIU Hai-ling
%A <br>刘芳
%A 刘树深
%A 刘海玲
%J 生态毒理学报
%D 2007
%I 
%X Ionic liquids(ILs)are claimed to be environmentally safe and very good non-volatile solvents for a wide range of applications. Although the information about physical, thermodynamic, kinetic or engineering data has been extended continuously, only little data with regard to the toxicity and ecotoxicity of ILs have been available until now. Using the microplate luminometer as testing equipment and the freshwater photobacteria--Vibrio-qinghaiensis sp.-Q67 as indication organism, the luminescence inhibition toxicities of 12 ionic liquids including C6H11BF4N2(S1), C8H15ClN2(S2), C8H15BF4N2(S3), C9H14BF4N(S4), C9H17BF4N2(S5), C9H17BrN2(S6), C11H13BF4N2(S7), C11H13ClN2(S8), C12H23BrN2(S9), C14H27BF4N2(S10), C14H27ClN2(S11), and C16H31ClN2(S12) and their mixtures to Q67 were determined. Obviously, there were 2 groups of mixtures, a high-toxicity group(H-set) with pEC50 > 4.5, including S9, S10, S11 and S12, and a low-toxicity group (L-set) with pEC50 < 3.5, including S1, S2, S3, S4, S5, S6, S7 and S8. The EC50 values of single compounds(from S1 to S12)revealed that the toxic order was S10>S12>S11>S9>S7>S8>S6>S3>S4>S2>S5>S1. The test mixtures were prepared using equivalent-effect concentration ratio(EECR)and uniform design concentration ratio(UDCR)method. It has been found that the toxicities of 8 test mixtures designed by the EECR and the H-set or L-set ILs can be accurately predicted by the dose-addition(DA)model. Also, the toxicities of 6 test mixtures constructed by the UDCR and the H-set ILs can be predicted by the DA model. However, the toxicities of 6 test mixtures constructed by the UDCR and the L-set ILs can't be effectively predicted by the DA or independent action(IA)model because there is an upwarp in the low-dose area of the dose-response curves.
%K ionic liquids
%K photobacteria
%K Vibrio-qinghaiensis
%K dose addition
%K independent action
%K mixture toxicity<br>离子液体
%K 发光菌
%K 青海弧菌
%K 剂量加和
%K 独立作用
%K 混合物毒性
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=3FF3ABA7486768130C3FF830376F43B398E0C97F0FF2DD53&cid=BEC1F4700DD66C14D137590A0896A0AD&jid=B98D390DF92C35E6DD1987675E4EE86E&aid=720A7341E8CFDEBB&yid=A732AF04DDA03BB3&vid=0B39A22176CE99FB&iid=0B39A22176CE99FB&sid=F260CE035846B3B8&eid=73579BC9CFB2D787&journal_id=1673-5897&journal_name=生态毒理学报&referenced_num=2&reference_num=29