%0 Journal Article
%T DNA-Protein Crosslinks Induced by Microcystin-LR in Hepatic Cells of Mice
%A DUAN Li-ju
%A ZHANG Hui-zhen
%A DONG Ling
%A CHENG Xue-min
%A CUI Liu-xin
%A <br>DUAN Li-ju
%A ZHANG Hui-zhen
%A DONG Ling
%A CHENG Xue-min
%A CUI Liu-xin
%J 生态毒理学报
%D 2008
%I 
%X 为探讨微囊藻毒素-LR致小鼠肝细胞的DNA-蛋白质交联作用，将20只昆明雄性小鼠随机分为4组：1个对照组和3个染毒组，采用腹腔注射进行染毒7d，染毒剂量分别为3.0、6.0和12.0μg·kg-1，检测小鼠肝细胞DNA-蛋白质交联程度. 结果显示，3.0、6.0和12.0μg·kg-1微囊藻毒素-LR均可导致小鼠肝细胞显著的DNA-蛋白质交联作用（与对照组相比，p<0.01，p<0.01，p<0.05），当微囊藻毒素为6.0μg·kg-1时，这种作用最明显.
%K microcytin-LR
%K mouse
%K hepatic cells
%K DNA-protein crosslinks<br>microcytin-LR
%K mouse
%K hepatic
%K cells
%K DNA-protein
%K crosslinks
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=3FF3ABA7486768130C3FF830376F43B398E0C97F0FF2DD53&cid=BEC1F4700DD66C14D137590A0896A0AD&jid=B98D390DF92C35E6DD1987675E4EE86E&aid=24AB0A80DE86EA6F718529246DD04928&yid=67289AFF6305E306&vid=38B194292C032A66&iid=B31275AF3241DB2D&sid=4AB4178709047BE3&eid=2E15A588990CC690&journal_id=1673-5897&journal_name=生态毒理学报&referenced_num=0&reference_num=14