%0 Journal Article
%T Experimental Research and Application of Zebrafish and Embryos in Toxicology<br>斑马鱼及其胚胎在毒理学中的实验研究与应用进展
%A WANG Jia-ji
%A Xu Chao
%A TU Yun-jie
%A FU Zheng-wei
%A LIU Wei-ping
%A <br>王佳佳
%A 徐超
%A 屠云杰
%A 傅正伟
%A 刘维屏
%J 生态毒理学报
%D 2007
%I 
%X Zebrafish has the inherent advantage compared with other model animals, and its use in scientific research is growing rapidly. In this review, we introduced the zebrafish genome, including forward genetic, reverse genetic and the application of zebrafish in drug discovery and human disease research; we also summarized the application of zebrafish in developmental biology. Finally, we reviewed the use of zebrafish in various toxicology research fields (acute toxicity, endocrine disruption, developmental toxicity, neurotoxicity, vascular research and cancer research).
%K genome
%K cell
%K toxicology
%K transgene
%K mutation<br>基因组学
%K 细胞
%K 毒理学
%K 转基因
%K 突变
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=3FF3ABA7486768130C3FF830376F43B398E0C97F0FF2DD53&cid=BEC1F4700DD66C14D137590A0896A0AD&jid=B98D390DF92C35E6DD1987675E4EE86E&aid=C9B339F7C9DF452E&yid=A732AF04DDA03BB3&vid=0B39A22176CE99FB&iid=0B39A22176CE99FB&sid=AE09EACBCD1B2A13&eid=5E25104E99903E8A&journal_id=1673-5897&journal_name=生态毒理学报&referenced_num=7&reference_num=118