%0 Journal Article
%T Permeation mechanism of a two-state Potassium channel<br>钾离子通道两态跳跃的通透机制
%A Wang XiangQun
%A Zhao TongJun
%A Song Yang
%A Zhan Yong
%A <br>王向群
%A 赵同军
%A 宋杨
%A 展永
%J 生物物理学报
%D 2005
%I 
%X A two-state hopping model was proposed for studying the permeation of ion channel. The Nernst equation in equilibrium and the Michaelis-Menten relation in steady state were derived from the two-state kinetic model. The current-voltage relationship obtained in the symmetrical solutions case was linear when the applied potential was less than 100 mV that satisfied Ohm's law at higher applied potentials. The conductance-concentration relationship exhibited the saturation property. Moreover the characteristic time reached the steady state of the KcsA channel was also discussed.
%K Potassium channel
%K Selectivity filter
%K Master equation<br>钾离子通道
%K 选择性过滤器
%K 主方程
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=E0C9D9BBED813D6674AC13E942EAC86D&aid=EFDBB7346A41CEE9&yid=2DD7160C83D0ACED&vid=659D3B06EBF534A7&iid=E158A972A605785F&sid=F50A8B5513721E1C&eid=E39A3F4E3A67639B&journal_id=1000-6737&journal_name=生物物理学报&referenced_num=0&reference_num=10