%0 Journal Article
%T PHOSPHOINOSITIDES AND CELLULAR EVENTS<br>磷酸肌醇家族与细胞功能
%A OUYANG Ying-shi
%A <br>欧阳英石
%J 生物物理学报
%D 2000
%I 
%X Signaling roles for phosphoinostides that function as precursors to generate second messengers upon agonist stimulation have been well characterized. Recent work has revealed that phosphoinositides can themselves serve as lipid second messengers to recruit their effector proteins to spatially localized membranes and regulate their assembly or activities. The interactions of phosphoinositides with proteins depend on pleckstrin homology(PH) domains, FYVE domains and phosphotyrosine-binding(PTB) domains.Cellular events in which phosphoinositides have been implicated include ion transport, membrane trafficking, signal transduction, cytoskeletal organization and nuclear gene regulation.
%K Phosphoinositides
%K Phosphoinositides-binding domains
%K Cellular events<br>磷酸肌醇
%K 脂质第二信使
%K 蛋白质结构域
%K 细胞功能
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=E0C9D9BBED813D6674AC13E942EAC86D&aid=F8B6A32BEEA59CDF&yid=9806D0D4EAA9BED3&vid=7801E6FC5AE9020C&iid=0B39A22176CE99FB&sid=64963996248CBF47&eid=38685BC770C663F2&journal_id=1000-6737&journal_name=生物物理学报&referenced_num=2&reference_num=8