%0 Journal Article
%T STUDIES ON THE SCAVENGING EFFECT OF TANSHINONE ON LIPID FREE RADICAL OF CARDIAC SARCOPLASMIC RETICULUM DURING PEROXIDATION<br>丹参酮对心肌肌质网脂质过氧化过程中脂类自由基的清除作用
%A Jiang Wen
%A Zhao Yan
%A Zhao Baolu
%A Wan Qian
%A Xin Wenjuan
%A <br>江文
%A 赵燕
%A 赵保路
%A 万谦
%A 忻文娟
%J 生物物理学报
%D 1994
%I 
%X The scavenging effect of natural antioxidant Salviol on lipid free radicals generated from lipid peroxidation of cardiac Sarcoplasmic Reticulum was investigated by the use of spin trapping technique and chemiluminescence methods. It was found that Tanshinone at a certain range of concentration could effectively protect SR from peroxidation. When the concentration of Tanshinone was more than 1mg/ml protein, its scavenging effect on lopid free radicals could reach 60%. However, the scavenging effect of Tanshinone on OH was very weak. It appears that the mechanism of the protection of Tanshinone against peroxidation of SR may be through breaking the chain reaCtions of peroxidation by scavenging lipid free radicals, but not preventing the initiation of peroxidation by scavenging the oxygen free radicals.
%K Natural antioxidant Sarcoplasmic reticulum Tanshinone Spin trapping Chemiluminescence Lipid peroxidation<br>天然抗氧化剂，丹参酮，肌质网，自旋捕集，化学发光，脂质过氧化
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=E0C9D9BBED813D6674AC13E942EAC86D&aid=921269908311B5AE49E2A16715E439B3&yid=3EBE383EEA0A6494&vid=F3090AE9B60B7ED1&iid=E158A972A605785F&sid=AF14A8B15FB15A64&eid=128B7AEF80A42C95&journal_id=1000-6737&journal_name=生物物理学报&referenced_num=3&reference_num=3