%0 Journal Article %T MORPHOLOGICAL AND ELECTROPHYSIOLOGICAL DEVELOPMENT OF NEONATAL RAT CORTICAL NEURON IN CULTURE
体外培养新生大鼠皮层神经细胞的形态及电学特性的演变 %A Yuan Huipin Liu Jinrong %A
袁惠品 %A 刘锦荣 %J 生物物理学报 %D 1993 %I %X There are three different morphological types of neuron, pyramidal-shaped neuron, stellate - shaped neuron and bipolar -shaped neuron. in the culture of neonatal rat cortex observed under the inverted phase contrast microscope (NIKON 810185. Japan).The results of intracellular microelectrode recording of stellate-shaped neuron indicated that its resting membrane potential increased significantly with the increase of culture age and the input resistance decreased since the second stage of culture (7-10 days). L-glutamate (extracellular pressure injection through microelectrode) caused stellate-shaped neuron depolarized and with the increase of culture age. the response ratio of the depolarization to L-glutamate among population of stellate-shaped neuron was increased. %K Neonatal rat Stellate-shaped neuron Resting membrane potential Input resistance L-Glutamate
神经细胞 %K 形态 %K 电学特性 %U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=E0C9D9BBED813D6674AC13E942EAC86D&aid=91EDEBB0B7AB2B06CF81221497692326&yid=D418FDC97F7C2EBA&vid=9CF7A0430CBB2DFD&iid=38B194292C032A66&sid=D98387EFB283C5E0&eid=BD7D27247C63490C&journal_id=1000-6737&journal_name=生物物理学报&referenced_num=1&reference_num=2