%0 Journal Article
%T Progress and prospect of electrospun silk fibroin in construction of tissue-engineering scaffold<br>丝素蛋白在电纺丝法构建组织工程支架中的应用进展
%A Ling Chen
%A Yabin Zhu
%A Yuanyuan Li
%A Yuxin Liu
%A Junyao Yu
%A <br>陈玲
%A 竺亚斌
%A 李媛媛
%A 刘玉新
%A 俞珺瑶
%J 生物工程学报
%D 2011
%I 
%X Silk fibroin is a natural macromolecular fibroin. It has broad prospects in tissue engineering application due to its good physical and mechanical properties and good biocompatibility. This paper reviews its chemistry structure, property, the usage as matrix of tissue-engineering scaffold using electrospinning technology, and the influence on growth, proliferation and function of vascular endothelial cell, smooth muscle cell, keratinocyte and fibroblast. It also addresses the advantages and disadvantages of silk fibroin applied in tissue engineering study like artificial vascular, skin, bone stent etc. The potential applications on esophageal tissue engineering and regenerative medicine were discussed.
%K silk fibroin
%K electrospinning technology
%K tissue engineering
%K scaffold construction<br>丝素蛋白，电纺丝，组织工程，支架构建
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A66E90C274451689E69F6F0291467824&aid=9880CD65C317F63DA0C4DA7A1A3AF077&yid=9377ED8094509821&vid=DB817633AA4F79B9&iid=B31275AF3241DB2D&sid=6D80B994DAB4686B&eid=2C8B50BA95995EA2&journal_id=1000-3061&journal_name=生物工程学报&referenced_num=0&reference_num=0