%0 Journal Article
%T Theoretical Evaluation on Antioxidant Activity of Components from Four Herbs<br>对九种天然产物清除自由基活性的理论评价
%A SHEN Liang
%A JI Hong-fang
%A CHAI Jian-guo
%A ZHANG Shan-fei
%A ZHANG Hong-yu
%A <br>申亮
%A 纪洪芳
%A 柴建国
%A 张善飞
%A 张红雨
%J 生物物理学报
%D 2005
%I 
%X Employing quantum chemistry method,the O-H bond dissociation enthalpies (BDEs) and ionization potentials (IPs) of nine natural products,scutellarin,pyromeconic acid,3,5-Dicafferoylquinic acid,erigoster B,salvianolic acid B,salviamiltiorrhiza,bioflavones,ginkgolides B,hydroxysafflor yellow A,extracted from four herbs,Erigeron brevisecapus Hand.Mazz,Salvia miltiorrhiza Bunge,Ginkgo biloba Linn and Carthamus tinctorius L,were calculated.Accordingly,the radical-scavenging activity of these components was evaluated.It was found that 3,5-dicafferoylquinic acid,erigoster B,salvianolic acid B and salviamiltiorrhiza were rather active to scavenge free radicals in non-polar solvents,while breviscap-ine B held much higher antioxidant activity than that of other eight components in polar solvent,which indicated that these compounds are promising to be developed as efficient drugs to treat radical-induced cardiovascular and cerebrovascular diseases.
%K Erigeron brevisecapus Hand
%K Mazz
%K Salvia miltiorrhiza Bunge
%K Ginkgo biloba Linn
%K Carthamus tinctorius L
%K Antioxidant
%K Quantum chemistry calculation<br>灯盏花
%K 丹参
%K 银杏
%K 红花
%K 抗氧化剂
%K 量子化学计算
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=E0C9D9BBED813D6674AC13E942EAC86D&aid=453849A6613B8FD9&yid=2DD7160C83D0ACED&vid=659D3B06EBF534A7&iid=94C357A881DFC066&sid=2E01F39B6CBD53DE&eid=302684F6FB4B24FF&journal_id=1000-6737&journal_name=生物物理学报&referenced_num=4&reference_num=25