%0 Journal Article
%T Establishment of xenograft mouse models to study human lung cancer by using in vivo imaging system<br>用于活体成像的小鼠肺癌移植瘤模型的建立
%A Haiyan Zhang
%A Yan Li
%A Zhe Wang
%A Biliang Zhang
%A <br>张海燕
%A 李艳
%A 王喆
%A 张必良
%J 生物工程学报
%D 2009
%I 
%X We established xenograft mouse models for studying human lung cancer by using an in vivo imaging system.We first transfected pGL4.17(luc2/neo) plasmid into human non-small lung cancer A549 cells and screened cell lines stably expressing a luciferase reporter gene with G418.Then we analyzed the correlation of luciferase activity and cells number by in vitro bioluminescence.Furthermore,we compared cell growth characteristics by cell counting.We selected suitable clones and inoculated subcutaneously into nude ...
%K luciferase
%K A549 cell
%K animal model
%K xenograft
%K in vivo imaging system<br>荧光素酶
%K A549细胞
%K 动物模型
%K 移植瘤
%K 活体成像
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A66E90C274451689E69F6F0291467824&aid=79C0A125D63D0285AE3E21408F3B9CD1&yid=DE12191FBD62783C&vid=C5154311167311FE&iid=5D311CA918CA9A03&sid=FE01B30EDB347E58&eid=004AE5CF627F0ACA&journal_id=1000-3061&journal_name=生物工程学报&referenced_num=2&reference_num=10