%0 Journal Article
%T Solution structure and antibacterial mechanism of two synthetic antimicrobial peptides<br>两种合成抗菌肽的结构及抗菌作用机理
%A Lin Yang
%A Meihua Fan
%A Xuezhu Liu
%A Mei Wu
%A Ge Shi
%A Zhi Liao
%A <br>杨林
%A 范美华
%A 刘雪珠
%A 武梅
%A 石戈
%A 廖智
%J 生物工程学报
%D 2011
%I 
%X Mytilin-derived-peptide-1(MDP-1) and mytilin-derived-peptide-2(MDP-2) are two truncated decapeptides with reversed sequence synthesized corresponding to the residues 20-29 of mytilin-1(GenBank Accession No.FJ973154) from M.coruscus.The objective of this study is to characterize the structural basis of these two peptides for their antimicrobial activities and functional differences,and to investigate the inhibitory mechanism of MDPs on Escherichia coli and Sarcina lutea.The structures of MDP-1 and MDP-2 in s...
%K mytilin-derived-peptide
%K artificial antimicrobial peptides
%K nuclear magnetic resonance
%K solution structure
%K transmitted electron microscopy (TEM)<br>mytilin-derived-peptide，人工抗菌肽，核磁共振，溶液结构，电镜分析
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A66E90C274451689E69F6F0291467824&aid=F437B1BF01E7F486FCF0371F5C502BD7&yid=9377ED8094509821&vid=DB817633AA4F79B9&iid=708DD6B15D2464E8&sid=FDE90279419513E0&eid=ECF40C1D1FB7C43B&journal_id=1000-3061&journal_name=生物工程学报&referenced_num=0&reference_num=24