%0 Journal Article
%T Essential genes, minimal genome and synthetic cell of bacteria: a review<br>细菌必需基因、最小基因组和合成细胞
%A Dongru Qiu
%A <br>邱东茹
%J 生物工程学报
%D 2012
%I 
%X Single-cell prokaryotes represent a simple and primitive cellular life form. The identification of the essential genes of bacteria and the minimal genome for the free-living cellular life could provide insights into the origin, evolution, and essence of life forms. The principles, methodology, and recent progresses in the identification of essential genes and minimal genome and the creation of synthetic cells are reviewed and particularly the strategies for creating the minimal genome and the potential applications are introduced.
%K essential genes
%K minimal genome
%K synthetic cell
%K virtual cell<br>必需基因
%K 最小基因组
%K 合成细胞
%K 虚拟细胞
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A66E90C274451689E69F6F0291467824&aid=13A5D5D02B8AA870F1823075FF9AD668&yid=99E9153A83D4CB11&vid=D3E34374A0D77D7F&iid=94C357A881DFC066&sid=DFBC046213B3DD86&eid=811ACA5D3673A764&journal_id=1000-3061&journal_name=生物工程学报&referenced_num=0&reference_num=0