%0 Journal Article
%T Analysis of Sodium Benzoate Biotoxicity by Atomic Force Microscope<br>应用原子力显微镜分析苯甲酸钠生物毒性
%A Mingqian Hu
%A Jiongkun Wang
%A Jiye Cai
%A Yangzhe Wu
%A Xiaoping Wang
%A <br>胡明铅
%A 王炯坤
%A 蔡继业
%A 吴扬哲
%A 王小平
%J 生物工程学报
%D 2008
%I 
%X Atomic force microscope (AFM) was used to study biotoxicity of food preservative sodium benzoate (SB) at the single cellular level. Lymphocyte morphology and membrane ultrastructure treated with SB at different concentrations and time were analyzed visually. As compared to the normal lymphocyte, the cell morphology and membrane was significantly changed and its ultrastructure was also complicated. After treated with SB, the Rp-v, Rq, Ra and values were changed. The statistical analysis of lymphocytes after treated with SB was studied, and discussed its mechanism.
%K atomic force microscope
%K sodium benzoate
%K lymphocyte
%K morphological structure<br>原子力显微镜
%K 苯甲酸钠
%K 淋巴细胞
%K 形态结构
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A66E90C274451689E69F6F0291467824&aid=07F96C3578D48A9DC60E09F6659224C8&yid=67289AFF6305E306&vid=B91E8C6D6FE990DB&iid=5D311CA918CA9A03&sid=1658FDEF8AE04907&eid=71F658B36F902583&journal_id=1000-3061&journal_name=生物工程学报&referenced_num=0&reference_num=22