%0 Journal Article
%T Paclitaxel induced apoptotic genes and pathways alterations: a review<br>紫杉醇诱导凋亡的信号传导通路及与凋亡相关的基因和蛋白
%A Dan Liu
%A Hong Kang
%A Chuanzhen Sun
%A Ye Xiao
%A Kai Zhao
%A <br>刘丹
%A 康宏
%A 孙传真
%A 肖野
%A 赵凯
%J 生物工程学报
%D 2013
%I 
%X Taxol has clinical efficacy on many malignant tumors, thus having a good market prospects. The anti-cancer mechanism of taxol is to arrest the cell cycle of tumor cells, leading to apoptosis. Based on our research over the years, we reviewed the latest developments in signaling pathways, the effects of related genes and proteins on apoptosis during paclitaxel-induced apoptosis process, including the paclitaxel-producing gene in microbial fermentation process, cyclin, telomerase of apoptosis.
%K paclitaxel
%K apoptosis
%K signaling transduction
%K apoptosis gene
%K associated protein<br>紫杉醇，细胞凋亡，信号传导，凋亡基因，相关蛋白
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A66E90C274451689E69F6F0291467824&aid=2DB3B6D3544EDEBDF067C84C5223ADC0&yid=FF7AA908D58E97FA&vid=771469D9D58C34FF&iid=0B39A22176CE99FB&sid=D59111839E7C8BDF&eid=1B97AE5098AEB49C&journal_id=1000-3061&journal_name=生物工程学报&referenced_num=0&reference_num=0