%0 Journal Article
%T Chronic high dose of insulin stimulates lipolysis in porcine adipocytes<br>慢性高剂量胰岛素刺激猪脂肪细胞脂肪分解
%A Yongqing Yang
%A Dapeng Ju
%A Mingtao Zhang
%A Gongshe Yang
%A <br>杨永青
%A 鞠大鹏
%A 张明涛
%A 杨公社
%J 生物工程学报
%D 2009
%I 
%X To explore the effect of chronic high dose of insulin on lipolysis in porcine adipocytes and the underlying molecular regulation mechanisms,we cultured primary porcine adipocytes and incubated them with different concentrations of insulin(0,200,400,800,1600 nmol/L) for 24?96 h in the absence or presence of specific protein kinase A(PKA) inhibitor or extracellular signal-related kinase(ERK) inhibitor.Then,we measured the glycerol release into the culture media as an indicator of the lipolysis,and observed th...
%K perilipin A<br>胰岛素
%K 猪脂肪细胞
%K 脂肪分解
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A66E90C274451689E69F6F0291467824&aid=79CCDABD9D1DA9A54B058FE5DDF3D9D0&yid=DE12191FBD62783C&vid=C5154311167311FE&iid=CA4FD0336C81A37A&sid=B483F22C9A5D8F55&eid=F9F44409142B7FC3&journal_id=1000-3061&journal_name=生物工程学报&referenced_num=0&reference_num=30