%0 Journal Article
%T Biochemical Stimulus Effects in Cell Cleavage<br>考虑生化刺激的细胞分裂的力学模型
%A AN Mei-Wen
%A WU Wen-Zhou CHEN Wei-Yi QU Hua TENG Wei-Zhong
%A <br>安美文
%A 吴文周
%A 陈维毅
%A 曲华
%A 滕维中
%A 太原理工大学应用力学研究所
%J 生物工程学报
%D 2004
%I 
%X A lot of experimental findings have confirmed that :Animal cells acquire a spherical shape just before the division; Under biochemical stimulus of mitotic apparatus aster the cells form a contractile ring in equator plane, and the mother cell divides into two daughter cells; meanwhile the total volume keeps constant. In Zinemanas and Nir's model the reorientation of microfilament and the visco-elasticity of cortex have been took into consideration. In our present work, the effective coefficient m due to biochemical stimulus was incorporated into the model, and the local distribution C was modified to diffuse with the plasma membrane motion. The numerical results showed that the formation of a contractile ring and parameters such as the surface tension in the furrow and internal pressure can be predicted successfully. Compared with Zinemanas and Nir's model, the results of our model are more correspondent with the experimental results. It can be concluded that the effective coefficient m has limited effects on the process control of cytokinesis.
%K active filament
%K cytokinesis
%K contractile ring
%K big deformation
%K tension<br>主动微丝
%K 胞质分裂
%K 收缩环
%K 大变形
%K 张力
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A66E90C274451689E69F6F0291467824&aid=3D740513F9F630A7&yid=D0E58B75BFD8E51C&vid=A04140E723CB732E&iid=94C357A881DFC066&sid=9409F3EB075DCD5B&eid=3D8AB54CA690066A&journal_id=1000-3061&journal_name=生物工程学报&referenced_num=0&reference_num=12