%0 Journal Article
%T Autophagy and Caveolin-1 in cancer: a review<br>肿瘤细胞的自噬和窖蛋白-1
%A Yan Liu
%A Yang Wang
%A Dan Shi
%A Wei Zou
%A <br>刘艳
%A 王洋
%A 史丹
%A 邹伟
%J 生物工程学报
%D 2012
%I 
%X Autophagy, is an essential cellular process involving self-degradation of intracellular components via the lysosome, which plays the Janus role in cancer initiation and progression. Caveolin-1, a marker protein of caveolae, functions as scaffolding protein mediating many physiological and pathological processes including caveolae biogenensis, vesicular transport, cholesterol homeostasis, signal transduction and tumorigenesis. Recently, many reports showed that autophagy of tumor cells associated with stromal Cav-1. In this article, we reviewed the role of autophagy and relationship with Cav-1 in tumorigenesis and cancer development.
%K 自噬，肿瘤，Caveolin-1，缺氧诱导因子1α，核因子κB
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A66E90C274451689E69F6F0291467824&aid=8A6EC9640C158E7B343DDDF25AF3D8B2&yid=99E9153A83D4CB11&vid=D3E34374A0D77D7F&iid=5D311CA918CA9A03&sid=F434A3C2A19884E7&eid=3D9E2C3DB640307A&journal_id=1000-3061&journal_name=生物工程学报&referenced_num=0&reference_num=0