%0 Journal Article %T A Study on the Pattern Recognition of Thermophilic and Mesophilic Proteins
嗜热和常温蛋白模式识别的研究 %A ZHANG Guang-Ya %A FANG Bai-Shan %A
张光亚 %A 方柏山 %J 生物工程学报 %D 2005 %I %X Pattern recognition of thermophilic and mesophilic proteins were studied through principle component analysis, partial least-square regression and BP neural network. The results showed that the fitting accuracy of the three methods was 92% , 95% and 98% , respectively. And the forecasting accuracy was 60% , 72.5% and 72.5%, respectively. The best forecasting accuracy for thermophilic proteins was 75%, and for mesophilic proteins was 85%. A mathematical model was established and the biological meaning of it was expatiated on, a new method to discriminate the thermophilic and mesophilic proteins based on their sequences was established here. %K pattern recognition %K principle component analysis %K partial least-square regression %K BP neural network %K thermostability
模式识别,主成分分析,偏最小二乘回归,BP神经网络,热稳定性 %U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A66E90C274451689E69F6F0291467824&aid=C77D7CDD95683FCA&yid=2DD7160C83D0ACED&vid=659D3B06EBF534A7&iid=B31275AF3241DB2D&sid=40700C9CB4E84E3B&eid=5357CC5E80802025&journal_id=1000-3061&journal_name=生物工程学报&referenced_num=0&reference_num=13