%0 Journal Article
%T Propionic Acid Fermentation by Propionibacterium freudenreichii CCTCC M207015 with a Fibrous-bed Bioreactor<br>利用纤维床反应器固定化发酵生产丙酸
%A Xiaohai Feng
%A Bo Wu
%A Xiaobo Shen
%A Hong Xu
%A <br>冯小海
%A 吴波
%A 沈晓波
%A 徐虹
%J 生物工程学报
%D 2008
%I 
%X The production of propionic acid by Propionibacterium freudenreichii CCTCC M207015 was investigated in a Fibrous-bed bioreactor (FBB). The FBB was constructed by packing spiral cotton fibrous and immobilized into a bioreactor. By applying this bioreactor to propionic acid fermentation, the propionic acid yield had a significant improvement and reached 20.41 g/L, compared with the cell-free culture of 14.58 g/L (40 g/L of glucose). At the same time, the glucose exhausting time decreased from 120 h to 60 h. Batch fermentations at various glucose concentrations were carried out with FBB. Based on the analysis of the time course of production, fed-batch fermentation was also applied to produce propionic acid with FBB, the maximal propionic acid yield reached 45.91 g/L, and the proportion of propionic acid to total acids was about 72.31%.
%K fibrous-bed bioreactor
%K Propionibacterium freudenreichii CCTCC M207015
%K propionic acid
%K fed-batch fermentation<br>纤维床反应器
%K Propionibacterium
%K freudenreichii
%K CCTCC
%K M207015
%K 丙酸
%K 补料发酵
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A66E90C274451689E69F6F0291467824&aid=00072BE4F785ABBBBC756C5CEA18EF74&yid=67289AFF6305E306&vid=B91E8C6D6FE990DB&iid=B31275AF3241DB2D&sid=6A12B9FCEF71AE29&eid=E062BF8B95A95FD2&journal_id=1000-3061&journal_name=生物工程学报&referenced_num=1&reference_num=10